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Italy Curbs China Influence Over Formula One Tiremaker Pirelli
Italy Curbs China Influence Over Formula One Tiremaker Pirelli
Italy’s government stepped in to limit the influence of China’s Sinochem over Formula One supplier Pirelli SpA, citing
2023-06-17 03:50
iOS 17.2: Update bringing host of new changes including Journal app and iPhone 15 Pro features
iOS 17.2: Update bringing host of new changes including Journal app and iPhone 15 Pro features
Apple is preparing a new update that will bring a host of new features to the iPhone. Some of the tools were announced in June, when Apple first showed off its major iOS 17 update, such as the long-awaited Journal app. That uses machine learning to understand what people have done in a day, and encourages them to write about their activities to remember them. Some are unexpected. That includes new updates to the iPhone 15 Pro’s action button: now, users can press the button to bring up a translate option, which shows a window and lets people speak text to have it appear in another language. The action button was introduced with the iPhone 15 Pro last month, as a replacement for the mute switch that can be mapped to any activity. Apple did not say then that it was planning to introduce new actions for that button. The new update also lets people add stickers as reactions on messages, collaborate on Apple Music playlists, redesigns the Apple TV app and some widgets, and more. iOS 17.2 was released as a developer beta update this week. It will likely make its way to everyone’s phones in November or December, though it will be possible to get it earlier by signing up to Apple’s public beta channel. Those on the public updates received their own update this week, in the form iOS 17.1. But the changes introduced with that update are more limited, such as new settings for the StandBy mode that shows when a phone is placed on its side and an AirDrop feature that lets transfers continue over the internet when devices are separated. Read More The Apple Watch feature everyone has been waiting for has finally arrived Apple’s plans for the future of AirPods might just have been revealed Apple TV+ and other subscriptions are about to get a lot more expensive
2023-10-28 01:15
How to Unlock Apex Legends Fuse Heirloom
How to Unlock Apex Legends Fuse Heirloom
The Apex Legends Fuse Heirloom is an electric guitar called The Razor's Edge that fans get by unlocking all 24 cosmetics in the Harbingers Collection Event.
2023-09-15 02:47
Meta considers paid subscription in EU for users to bypass targeted ads
Meta considers paid subscription in EU for users to bypass targeted ads
Instagram and Facebook users in the European Union may soon be able to opt out of targeted ads if they pay for a monthly subscription.
2023-10-04 04:50
Scientists believe they have found a cure for alcoholism
Scientists believe they have found a cure for alcoholism
Alcohol addiction ruins millions of lives every year, but scientists may have found a cure for this terrible affliction. A new treatment for alcohol use disorder (AUD) has been trialled in monkeys with impressive results and, if these translate to human trials, the impact could be monumental. A team of neuroscientists and physiologists from across the US tested a new type of gene therapy to see if they could directly target the underlying brain circuitry associated with sustained heavy drinking. As they noted, in the journal Nature Medicine, people suffering from AUD commonly return to alcohol use even if they attempt to quit. This is largely to do with what’s known as mesolimbic dopamine (DA) signalling – meaning how the central nervous system circuit communicates the feelgood neurotransmitter dopamine. A protein called glial-derived neurotrophic factor (GDNF) is key to keeping these neurons in this reward circuitry functioning. However, experts have found that levels of GDNF are reduced in people with AUD during periods of alcohol abstinence, most notably in a region of the brain called the ventral tegmental area (VTA), as IFLScience notes. Therefore, the researchers decided to test whether using gene therapy to deliver more GDNF to the VTA could help reinforce this crucial dopaminergic signalling and prevent patients from suffering an alcoholic relapse. The team of scientists explained how alcohol consumption in non-addicts prompts the release of dopamine, creating a pleasurable buzz feeling, but chronic alcohol use causes the brain to adapt and stop releasing so much dopamine. “So when people are addicted to alcohol, they don’t really feel more pleasure in drinking,” Dr Kathleen Grant, a senior co-author of the study, said in a statement. “It seems that they’re drinking more because they feel a need to maintain an intoxicated state.” For their research, Dr Grant and her colleagues used eight rhesus macaque monkeys, who were exposed to increasing concentrations of alcohol over four 30-day “induction” periods. The monkeys then had free access to alcohol and water for 21 hours a day for six months, during which they developed heavy drinking behaviours. This was then followed by a 12-week abstinence phase, with the GDNF treatment performed four weeks in for half of the subjects. The gene therapy was delivered using a a viral vector containing a copy of the human GDNF gene injected directly into the primate’s VTA, according to IFLScience. And the results were truly jaw-dropping. “Drinking went down to almost zero,” Dr Grant said. “For months on end, these animals would choose to drink water and just avoid drinking alcohol altogether. They decreased their drinking to the point that it was so low we didn’t record a blood-alcohol level.” The most exciting aspect of their findings is the suggestion that gene therapy could offer a permanent solution for people with the most severe cases of AUD. This will be a welcome glimmer of hope to many, given that some 29.5 million people were diagnosed with AUD in the US alone in 2021, according to the National Institute on Alcohol Abuse and Alcoholism. Of these 29.5 million sufferers, almost a million (894,000) were aged between 12 and 17. It’ll likely be some time before we know for sure whether the gene therapy can be rolled out in humans, but it’s an important first step in tackling this devastating disorder. Sign up for our free Indy100 weekly newsletter Have your say in our news democracy. Click the upvote icon at the top of the page to help raise this article through the indy100 rankings.
2023-09-01 20:52
Apple Sharply Cuts Vision Pro Headset Production Target, FT Says
Apple Sharply Cuts Vision Pro Headset Production Target, FT Says
Apple Inc. is cutting production targets for its long-awaited mixed-reality Vision Pro headset due to difficulties in producing
2023-07-03 12:58
Chinese rocket that hurtled into the Moon was carrying a ‘secret object’
Chinese rocket that hurtled into the Moon was carrying a ‘secret object’
A mysterious object crashed into the Moon last year, and scientists think they’ve finally figured out what it was. On March 4, 2022, a piece of space junk hurtled towards the surface of our celestial companion, leaving behind not one but two craters – prompting speculation as to what exactly the manmade object was. And now, in a paper published in the Planetary Science Journal, a team of researchers at the University of Arizona (UArizona) have offered “definitive proof” that it was a booster from a Chinese space rocket that had spent several years hurtling through space. But the most interesting part of all this? The defunct piece of spacecraft was apparently carrying a secret cargo. Initially, based on its path through the sky, the UArizona team thought it was an errant SpaceX Falcon 9 rocket booster from a 2015 launch. However, after analysing how precise light signals bounced off its surface, they later concluded that it was more likely to be a booster from a Chang'e 5-T1 – a rocket launched back in 2014 as part of China’s lunar exploration programme. And yet, the Chinese space agency denied ownership, insisting that their rocket booster burned up in the Earth's atmosphere upon re-entry. But the US Space Command refuted this claim by revealing that the rocket’s third stage never re-entered the planet’s atmosphere. Furthermore, two key pieces of evidence gathered by the UArizona researchers suggested that there was more to the object than just a simple abandoned rocket booster. Firstly, the way it reflected light. The paper’s lead author, Tanner Campbell, explained in a statement: "Something that's been in space as long as this is subjected to forces from the Earth's and the moon's gravity and the light from the sun, so you would expect it to wobble a little bit, particularly when you consider that the rocket body is a big empty shell with a heavy engine on one side. “But this was just tumbling end-over-end, in a very stable way." In other words, the rocket booster must have had some kind of counterweight to its two engines, each of which would have weighed around 545kg (1,200lbs) without fuel. The stability with which the object rotated led Campbell and his colleagues to deduce that “there must have been something more mounted to [its] front”. Secondly, the team were struck by the impact the booster left when it slammed into the Moon. It created two craters, around 100ft (30.5 metres) apart, instead of one, which, according to Campbell was very unusual. He pointed out that the craters left behind by Apollo rockets are either round, if the object came straight down, or oblong if it crashed down at a shallow angle. "This is the first time we see a double crater," he said. "We know that in the case of Chang'e 5 T1, its impact was almost straight down, and to get those two craters of about the same size, you need two roughly equal masses that are apart from each other." And yet, despite the rigour of their investigation, the UArizona team have been unable to identify what exactly this additional object was. "We have no idea what it might have been – perhaps some extra support structure, or additional instrumentation, or something else," Campbell admitted. "We probably won't ever know." Sign up for our free Indy100 weekly newsletter Have your say in our news democracy. Click the upvote icon at the top of the page to help raise this article through the indy100 rankings
2023-11-21 20:25
How many Apple products can you buy for one Vision Pro headset?
How many Apple products can you buy for one Vision Pro headset?
At today's WWDC event, Apple made jaws drop when it announced that its newest product,
2023-06-06 09:55
Mouser-Backed DS PENSKE Formula E Racing Team Wraps-Up Another Thrilling Season
Mouser-Backed DS PENSKE Formula E Racing Team Wraps-Up Another Thrilling Season
DALLAS & FORT WORTH, Texas--(BUSINESS WIRE)--Aug 7, 2023--
2023-08-07 23:20
GameStop is changing its rewards program — save $10/year if you sign up before June 27
GameStop is changing its rewards program — save $10/year if you sign up before June 27
SAVE $10: GameStop is overhauling its PowerUp Rewards membership program (soon to be named GameStop
2023-05-25 01:46
Asmongold defends xQc amid backlash over $100M Kick deal but fans nitpick his 'truths'
Asmongold defends xQc amid backlash over $100M Kick deal but fans nitpick his 'truths'
Asmongold defended xQc while discussing why he didn't agree with the criticisms leveled at the latter but not everyone agreed with him
2023-06-23 22:27
iPhone 15 charging speed may be just as slow as iPhone 14
iPhone 15 charging speed may be just as slow as iPhone 14
There is plenty to look forward to with the new iPhone 15, but faster charging
2023-09-19 00:49