Scientists in Israel have created a model of a human embryo from stem cells, without using sperm, eggs or a womb. A team at Israel's Weizmann Institute of Science made the model, which resembles an embryo at day 14, when it acquires internal structures but before it lays down the foundations for body organs, and the work was published in the journal Nature. But the scientists involved said it would take a long time yet to create an embryo from scratch. Team leader Jacob Hanna said the team took stem cells derived from adult human skin cells, as well as others cultured in the lab, then reverted the cells to an early state.They then manipulated them to make a model of an embryo, rather than an actual or synthetic one. "The question is, when does an embryo model become considered an embryo? When that happens, we know the regulations. At the moment we are really, really far off from that point," Hanna said. However, they said the work could open the door to new ways to test the effect of drugs on pregnancies, better understand miscarriages and genetic diseases, and maybe grow transplant tissues and organs. "They are not identical. There are differences from human embryos, but still, this is the first time, if you open an atlas or a textbook, you can say - yeah I can really see the similarity between them," said Hanna. "In about 1 percent of the aggregates we can see that the cells start differentiating correctly, migrating and sorting themselves into the correct structure, and the farthest we could get is day 14 in human embryo development," he said. Their next goal, Hanna said, is to advance to day 21 and also reach a threshold of a 50 per cent success rate. Magdalena Żernicka-Goetz, a professor of development and stem cells at the University of Cambridge, said the study joins six other similar human embryo-like models published from teams around the world this year, including from her lab. "None of these models fully recapitulate natural human development but each adds to ways in which many aspects of human development can now be studied experimentally," she said. Sign up to our free Indy100 weekly newsletter Have your say in our news democracy. Click the upvote icon at the top of the page to help raise this article through the indy100 rankings.

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Humane has launched its AI Pin, one of the world’s most hyped tech products, and it has immediately made a public mistake. The AI Pin has been the subject of speculation promoted by Humane, a company that has remained somewhat mysterious and includes designers and executives who have worked at Apple and Microsoft. The system is intended to be attached to clothing and then makes use of a range of microphones, speakers and a display that can shine onto its owners hand to give information. That information is provided by artificial intelligence systems built on technology from ChatGPT creator OpenAI and Microsoft. The pin costs $699 and will be available later this year. It has been promoted by its president Imran Chaudhri as a response to both the prevalence of phones and the future of mixed-reality headsets, instead aiming to allow people to engage with the world around them. One of the features intended to do that is access to artificial intelligence systems that can be used to get answers to questions. Users can just press the AI Pin and speak into the air, which will then allow the computer to access the internet and show an answer. During its reveal event, executives showed the pin being used to answer one such question. “I can also use it to ask questions, like: when is the next eclipse, and where is the best place to see it?”, representatives said, explaining that it would be answered by “an AI browsing the web, or grabbing knowledge from all over the internet”. The AI Pin is then showed answering by saying that the best place to view the next total solar eclipse, in April 2024, would be Exmouth in Australia or East Timor. But next year’s solar eclipse will in fact be visible in North America, and in fact has been given the name “the Great North American Eclipse”. It will not be at all visible in Australia, and can only be seen in Mexico, the US and Canada. The system may have made the mistake because a total solar eclipse earlier this year was in fact best viewed from Exmouth and East Timor. That eclipse, in April, brought widespread coverage to the small Australian town – and that coverage was presumably used to train the artificial intelligence system that answered the question. Humane did not say which assistant was being used for that answer. The AI Pin is built specifically to call on a number of different assistants depending on what question is asked. The error recalls a similar error made by Google’s Bard chatbot when it was introduced at the beginning of the year. An ad showed Bard being asked about interesting discoveries by Nasa’s James Webb Space Telescope, and replying that it had taken “the very first pictures of a planet outside of our own solar system” – which is not true. At the time, many noted that the error highlighted a central error with large language models. The systems tend to “hallucinate” – or confidently state falsehoods – and have no real way of being able to check whether the information they are given is true. Read More You can finally use one feature of the Apple Vision Pro headset – sort of ChatGPT creator mocks Elon Musk in brutal tweet Call of Duty launch sparks record traffic on broadband networks

ATLANTA--(BUSINESS WIRE)--Jul 18, 2023--

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