Fly.io, a tech startup whose public cloud infrastructure enables developers to deploy applications, has raised $70 million in

The controversial Rosebank oil and gas field in the UK North Sea got the go-ahead on Wednesday, despite

By Jeff Mason LIVE OAK, Florida (Reuters) -President Joe Biden traveled to Florida on Saturday to survey the destruction from

Top G expressed his surprise and wondered if the boy was indeed 13 years old

Valorant is not in the Soul Fighter event on July 20. League of Legends, Teamfight Tactics, Wild Rift, and Legends of Runeterra are the participating Riot Games titles.

Archaeologists have found a rare cold bath below the 18th-century Bath Assembly Rooms. The rooms, completed in 1771, were fashionable places of entertainment, conversation, dancing and gambling and cold baths were seen as good for people's health. The cold bath is in the centre of a suite of three rooms beneath one end of the ballroom. It has dressing rooms on either side. The excavation involved removing a later floor that had been installed over the cold bath and removing tonnes of rubble to reveal steps down into it. Bruce Eaton, of Wessex Archaeology, which oversaw the excavation, told the Guardian: “Although historical records indicated that there was a cold bath buried beneath the Bath Assembly Rooms, we had no idea what preservation of the bath would be like. “The building suffered damage at the hands of the Luftwaffe and the rooms were remodelled in the late 20th century but, after carefully excavating tonnes of concrete and rubble, we saw the original structure emerge in its entirety. “It’s tremendous to be able to piece together this rare archaeological evidence of an 18th-century cold bath with social historical accounts from the time.” Tatjana LeBoff, a project curator at the National Trust, said: “The cold bath at the assembly rooms is highly unusual. It is a rare, if not unique, surviving example, and possibly it was the only one ever built in an assembly room.” The trust was researching records, letters, diaries and other documents to discover more about the cold bath, she said. Sign up to our free Indy100 weekly newsletter Have your say in our news democracy. Click the upvote icon at the top of the page to help raise this article through the indy100 rankings.

MCLEAN, Va.--(BUSINESS WIRE)--Jun 2, 2023--

As short sellers target traditional green stocks being hammered by inflation, an executive at the fund management arm

BEIJING--(BUSINESS WIRE)--May 27, 2023--

Dubai’s financial regulator warned that global watchdogs need to step up talks with each other to avoid “bad

Google says it has made a significant step in identifying disease-causing genes, which could help spot rare genetic disorders. A new model named AlphaMissense is able to confidently classify 89 per cent of all possible “missense” variants in genes, identifying whether they are likely to cause diseases or benign. That compares with just 0.1 per cent of all missense variants that have been confidently classified by human experts. Missense variants happen when a single letter is substituted in the DNA, which in turn leads to proteins with a different amino acid. That small change can have significant effects – Google likened it to the way that changing a letter in one word can change the meaning of the whole sentence. Most of those variants are benign: the average person has more than 9,000 of them. But some of them can be disastrous, leading to rare genetic diseases. The new AlphaMissense looked at existing information about missense variants, and how commonly they are seen in humans and closely-related primates. It looked for those that were rarely seen, classifying them as pathogenic, and from that was able to use that information to analyse other protein sequences – giving not just a verdict on whether they were likely to cause problems, but also how confident it was. Experiments, conducted by humans, which look to find those mutations are expensive and slow: they require people to examine each unique protein and designed separately. Google says that the new system means that researchers can “preview” those results for thousands of proteins at a time, helping them decide where to focus. The company has used its systems to release a vast catalogue of “missense” mutations, so that researchers can learn about what effect they have. In some cases, those variations can lead to conditions such as cystic fibrosis, sickle-cell anaemia, or cancer, and understanding them could be key to researchers studying ways to treat or prevent those diseases. It is just the latest health breakthrough from Google’s Deepmind division, which is looking to use artificial intelligence to both identify and treat a variety of conditions. The new system was built on AlphaFold, the breakthrough model that helped unfold proteins, the building blocks of life. The research is described in a new paper, ‘Accurate proteome-wide missense variant effect prediction with AlphaMissense’, published in the journal Science. The catalogue is being made “freely available to the research community”, Google said, and the company will release the code behind the AI system. Read More BBC removes some Russell Brand content as monetisation suspended on YouTube Google Bard can now link to Gmail and other apps to help with responses Long-form video content is here to stay, says YouTube UK boss

After returning to New York from Oslo in late May, Harley Hendrix noticed her suitcase containing a cherished